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目的观察无创双水平气道正压通气(BiPAP)辅助治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法将我院RICU的84例COPD合并Ⅱ型呼吸衰竭患者,随机分为无创通气组和常规治疗组。两组均予常规药物治疗。无创组辅以BiPAP无创通气,常规组予鼻导管吸氧,观察治疗2 h前后动脉血气的变化及无创通气对患者插管率的影响。结果相对于常规治疗组,BiPAP无创通气2 h可有效纠正呼吸性酸中毒,降低PCO2,提高PO2,降低插管率(P均<0.05)。结论 BiPAP无创通气可缓解COPD合并Ⅱ型呼吸衰竭患者呼吸困难,改善血气,降低气管插管率。
Objective To observe the curative effect of noninvasive bi-level positive airway pressure (BiPAP) in the treatment of chronic obstructive pulmonary disease (COPD) complicated with type Ⅱ respiratory failure. Methods Eighty-four COPD patients with type Ⅱ respiratory failure in our hospital were randomly divided into non-invasive ventilation group and conventional treatment group. Both groups were given conventional drug treatment. Non-invasive group supplemented with BiPAP noninvasive ventilation, conventional group nasal catheter oxygen, 2 h after treatment of arterial blood gas changes and noninvasive ventilation on the intubation rate. Results Compared with the conventional treatment group, BiPAP non-invasive ventilation for 2 h could effectively correct respiratory acidosis, reduce PCO2, increase PO2 and decrease intubation rate (all P <0.05). Conclusion Noninvasive ventilation with BiPAP can relieve dyspnea, improve blood gas and reduce intubation rate in COPD patients with type Ⅱ respiratory failure.