“药物副作用”一词,其定义不确切,最近使用“药物有害反应”(adverse drug reaction)一词。药物引起有害反应的机制有多种,其中作为皮质类固醇治疗的适应症,主要是药物所致之变态反应。然而,在药物有害反应中,属于变态反应者估计不到10％。适于类固醇治疗的药物有害反应者不多,主要限于变态反应、药物引起的严重的脏器损害或症状迁延的情况下使用。使用类固醇制剂时,应充分考虑到类固醇对原有疾病的影响以及类固醇本身的有害反应,而且 The term “drug side effects”, which is not defined precisely, recently used the term “adverse drug reaction.” Drugs cause harmful reactions in a variety of mechanisms, which as corticosteroid treatment indications, mainly drug-induced allergy. However, in the case of adverse drug reactions, it is estimated that less than 10% are allergic. Drugs suitable for steroid therapy are not many harmful reactions, mainly limited to allergies, drug-induced severe organ damage or symptoms of prolonged use. The use of steroid preparations should take full account of the steroid effects on the original disease and steroid itself harmful reactions, and