口服脊髓灰质炎减毒活疫苗(OPV)是世界卫生组织(WHO)推荐用于消灭脊灰的首选疫苗。但服用OPV可能引发个别的疫苗相关麻痹型脊髓灰质炎病例(vaccine-associated paralytic poliomyelitis,VAPP)。2007年我市曾发生1例VAPP,为了解VAPP发生的影响因素,探讨降低VAPP发生率的有效措施,我们对该病例的发病、诊断及其调查处理情况进行报告。 Oral oral live attenuated polio vaccine (OPV) is recommended by the World Health Organization (WHO) for the eradication of polio vaccine of choice. But taking OPV may trigger individual vaccine-associated paralytic poliomyelitis (VAPP). In 2007, one case of VAPP occurred in our city. To understand the influencing factors of VAPP and to explore effective measures to reduce the incidence of VAPP, we report the incidence, diagnosis and investigation of the case.