目的　观察As2 O3 对APL患者骨髓红细胞系的影响 ,为临床安全用药 ,患者平稳渡过初治期提供依据。方法　 3 0例初治的APL患者经As2 O3 治疗后观察血象、骨髓象的情况。结果　 6周以内骨髓红细胞系受抑 ,以后则恢复造血 ,甚至旺盛。结论　As2 O3 治疗APL头 6周以内的贫血主要靠输血、造血原料 ,6周以后仍需补充造血原料。 Objective To observe the effect of As2O3 on bone marrow erythrocyte cell line in patients with APL and to provide a basis for clinical safe medication and smooth transition of patients with initial stage. Methods Thirty cases of newly diagnosed APL patients were treated with As 2 O 3 and the blood and bone marrow were observed. Results Within 6 weeks, myeloid erythrocyte was suppressed, then hematopoietic was restored or even exuberant. Conclusion As2 O3 treatment of APL within 6 weeks of anemia mainly rely on blood transfusion, hematopoietic raw materials, still need to add hematopoietic raw material after 6 weeks.