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为探讨肝细胞癌(HCC)组织和正常人各组织转铁蛋白受体(TCR)的表达,明了TFR在HCC组织中表达的相对特异性程度及TCR能否作为HCC的肿瘤标记物和导向治疗的靶,作者应用TFR单克隆抗体WuT9和OKT_9,以亲和素生物素过氧化物酶结合物方法,对30例HCC组织和6例正常人务器官组织TFR的表达进行了研究。结果表明,HCC表达大量的TFR,癌周间质细胞不表达,癌巢深染棕色,癌周间质免疫染色阴
To investigate the expression of transferrin receptor (TCR) in hepatocellular carcinoma (HCC) tissues and normal human tissues, it is clear whether the relative specificity of TFR expression in HCC tissues and TCR can be used as tumor markers and targeted therapy for HCC. For the target, the authors used TFR monoclonal antibodies WuT9 and OKT_9 to study the expression of TFR in 30 HCC tissues and 6 normal human organ tissues using avidin biotin peroxidase conjugate method. The results showed that HCC express a large number of TFR, cancer cells do not express interstitial cells, cancer nests are dark brown, cancerous interstitial immunostaining