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本文用被动血凝集试验和白细胞移行抑制试验,检测了72例老年性白内障成熟期患者手术前、后对晶体蛋白的体液免疫和细胞免疫反应,并以32例无白内障无眼部炎症者作为对照组。结果说明白内障囊内摘出术后,对晶体蛋白的体液免疫反应100%无改变,而细胞免疫反应则有40%从阳性变为阴性。白内障囊外摘出术后,对晶体蛋白的体液免疫反应95.23%无改变,而细胞免疫反应则有21.43%从阳性变为阴性,有7.14%从阴性变为阳性。从这初步的结果,我们建议在白内障囊外摘出术前检查患者对晶体蛋白的免疫反应,手术后如果有炎症反应产生,应重复此项检查,以便考虑使用免疫抑制剂治疗或手术清除晶体残留物。
In this paper, passive blood agglutination test and leukocyte metastasis inhibition test were used to detect the humoral and cellular immune responses of crystal proteins in 72 mature cataract patients before and after surgery. 32 patients with no cataract without ocular inflammation Control group. The results showed that after the removal of cataract capsule, the humoral immune response to crystal protein 100% unchanged, while the cellular immune response was 40% from positive to negative. After extracapsular cataract extraction, there was no change of humoral immune response to crystal protein 95.23%, while the cellular immune response was changed from positive to negative 21.43%, 7.14% from negative to positive. From this preliminary result, we recommend that patients be examined for cytoprotein immunoreactivity before extracapsular cataract extraction, and if there is an inflammatory response after surgery, this test should be repeated in order to consider the use of immunosuppressive agents or surgical removal of residual crystals Things.