本品为氨基甲酸酯的衍生物。合成本品由2-苯基-1,3-丙二醇与氨甲酸甲酯进行酯交换反应而制得[J MedChem 1969,12(3)∶462]。药理本品为低毒性的具独特的抗惊厥作用谱的抗癫痫药。小鼠口服给药,本品抗超强电休克(MES)的ED_(50)与最小神经毒性的TD_(50)相距很大,其比值为19.05(ED_(50)/TD_(50));大鼠的ED_(50)/TD_(50)值大于63。动物试验中,本品显示了比苯妥因或乙 This product is carbamate derivatives. Synthesis of the goods from 2-phenyl-1,3-propanediol and methyl carbamate transesterification [J MedChem 1969,12 (3): 462]. Pharmacology This product is a low toxicity antiepileptic drug with a unique spectrum of anticonvulsant. In mice, the ED 50 of the anti-super electrostimulation (MES) and the minimal neurotoxicity TD 50 (50) were far apart, with a ratio of 19.05 (ED 50 / TD 50) Rat ED_ (50) / TD_ (50) values ​​greater than 63. Animal tests, the product shows than phenytoin or B