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在培养的Wistar大鼠心室肌细胞上,用膜片钳法证明齐墩果酸型人参皂甙单体R0200μmol·mL-1对L,B,T三型钙通道的单通道活动均无影响;用电子自旋共振法证明R030μmol·mL-1不能抑制黄嘌呤0.42mmol·L-1-黄嘌呤氧化酶5.3nmol·L-1所致的自由基含量增多。确切证明R0既无钙通道阻滞作用,也无抗自由基作用。
On the cultured Wistar rat ventricular myocytes, the patch-clamp method was used to prove that single-channel activities of L-type, B-type and T-type calcium channels were not affected by R0200μmol · mL-1 of oleanolic acid type ginsenoside. Electron spin resonance method proved R030μmol · mL-1 can not inhibit xanthine 0.42mmol · L-xanthine oxidase 5.3nmol·L-1 induced by free radicals increased. It is proved that R0 has neither calcium channel block effect nor anti-free radical effect.