抗癌药顺铂(简称CDDP)常用于治疗恶性肿瘤。其耳毒性的发生率为5.8～90％,临床表现为高频听力损失及耳鸣。我们单用顺铂或与放疗综合治疗食管癌202例,对其中30例于治疗前后行听力检查,现对其结果进行简要分析。 一、资料与方法 30例均为食管鳞状上皮癌二期患者,男21例,女9例。年龄35～67(平均56)岁。近期无耳毒药物应用史。 Anti-cancer drug cisplatin (referred to as CDDP) commonly used in the treatment of malignant tumors. The incidence of ototoxicity is 5.8 to 90%, the clinical manifestations of high-frequency hearing loss and tinnitus. We use cisplatin alone or with radiotherapy and comprehensive treatment of esophageal cancer in 202 cases, of which 30 cases before and after treatment, hearing tests, the results of a brief analysis. First, the data and methods 30 cases were esophageal squamous cell carcinoma of the second phase, 21 males and 9 females. Age 35 ~ 67 (average 56) years old. No recent history of application of ototoxic drugs.