目的:评价Seldinger法穿刺心包留置中心静脉导管引流心包积液的临床疗效及安全性。方法:45例心包积液患者用Seldinger法经皮穿刺,留置中心静脉导管,进行引流、注射药物等治疗。结果:45例患者均安全置管引流,临床症状明显改善,未发生严重并发症。结论:Seldinger法穿刺心包留置中心静脉导管引流心包积液是安全、有效、方便的治疗方法。 OBJECTIVE: To evaluate the clinical efficacy and safety of Seldinger’s puncture of pericardium for central venous catheter drainage pericardial effusion. Methods: 45 cases of pericardial effusion with Seldinger percutaneous puncture, indwelling central venous catheter, drainage, injection of drugs and other treatment. Results: All the 45 patients were safely placed and drained. The clinical symptoms were significantly improved without serious complications. Conclusion: The Seldinger method of puncture of the pericardial catheter for central venous drainage is a safe, effective and convenient treatment.