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视网膜母细胞瘤(Rb)多见于儿童眼部恶性肿瘤。Rb分遗传型和非遗传型,约1～5%的Rb病人有13号染色体1区4带(13q14)缺失。无论是遗传型或非遗传型Rb,其发生都与13q14位点的突变有关。此外,还发现
Retinoblastoma (Rb) more common in children with ocular malignancies. Rb subgenotype and non-genetic type, about 1 ~ 5% of Rb patients have 13 chromosome 1 zone 4 band (13q14) deletion. Whether genetic or non-genetic Rb, its occurrence is associated with the 13q14 mutation. In addition, also found