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目的了解江西省使用的乙型肝炎疫苗的安全性。方法分析江西省2010-2013年通过全国疑似预防接种异常反应信息管理系统收集到的与接种乙型肝炎疫苗有关的AEFI数据。结果江西省2010-2013年共报告与接种乙型肝炎疫苗有关的AEFI病例462例,报告发生率为5.39/10万,其中异常反应67例,报告发生率为0.78/10万。异常反应病例中过敏性皮疹最多,有39例,报告发生率为4.55/100万。结论江西省使用的乙型肝炎疫苗不良反应报告发生率未超过全国平均水平,具有较好的安全性。
Objective To understand the safety of hepatitis B vaccine used in Jiangxi Province. Methods AEFI data related to hepatitis B vaccination collected from Jiangxi Province in 2010-2013 through an information management system for suspected anaphylaxis in Jiangxi Province were collected. Results A total of 462 AEFI cases were reported in Jiangxi Province during 2010-2013. The reported incidence was 5.39 / 100 000, among which 67 cases were abnormal and the reported rate was 0.78 / 100 000. The most frequent anaphylactic rash was in 39 patients, with a reported incidence of 4.55 / 1 million. Conclusions The incidence of adverse reactions of hepatitis B vaccine used in Jiangxi Province does not exceed the national average level, and has good safety.