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每天给大鼠腹腔注射氯化锰15mg/kg,连续60天及84天。结果染锰大鼠睾丸重量下降(P<0.01),睾丸脏器系数也明显降低(P<0.01);血清锰虽无明显增高,但睾丸组织中的锰含量却增高;光镜检查:睾丸曲细精管呈不同程度的变性,管内生精细胞数目减少、缺如,精子形成少或无。
Rats were intraperitoneally injected with 15 mg / kg manganese chloride daily for 60 days and 84 days. Results The weight of testis decreased (P <0.01) and the coefficient of testicular organ significantly decreased (P <0.01). The content of manganese in serum increased but the level of manganese in testis increased. Check: testicular seminiferous tubules were varying degrees of degeneration, the number of spermatogenic cells to reduce, absent, less or no sperm formation.