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目的评价乌拉地尔与多巴酚丁胺、多巴胺、呋塞米合用治疗难治性心力衰竭的疗效。方法98例难治性心力衰竭病人分为三组,对照组32例应用洋地黄类药物、利尿剂、硝酸甘油等常规治疗;乌拉地尔组33例在对照组基础加乌拉地尔;联合治疗组33例在乌拉地尔组基础上加用多巴酚丁胺、多巴胺、呋塞米。结果联合治疗组的总有效率(94%)高于乌拉地尔组(85%),P(0.05;乌拉地尔组亦高于对照组(63%),P(0.05。结论乌拉地尔治疗难治性心力衰竭效果显著,与多巴酚胺、多巴胺、呋塞米合用疗效更佳。
Objective To evaluate the efficacy of urapidil combined with dobutamine, dopamine and furosemide in the treatment of refractory heart failure. Methods 98 cases of refractory heart failure patients were divided into three groups, the control group of 32 cases of digitalis drugs, diuretics, nitroglycerin and other conventional treatment; 33 cases of urapidil group in the control group plus urapidil; combination therapy Group 33 patients in the urapidil group on the basis of the use of dobutamine, dopamine, furosemide. Results The total effective rate (94%) in the combined treatment group was significantly higher than that in the urapidil group (85%), P (0.05), and also higher in the urapidil group than in the control group (63% Refractory heart failure effect is significant, and dobutamine, dopamine, furosemide combined effect is better.