NG2细胞是新发现的一类广泛存在于成熟和发育期中枢神经系统的胶质细胞群体。这些细胞表面表达NG2硫酸软骨素蛋白多糖,因而常被称作NG2细胞。随着NG2细胞形态学研究的深入,NG2胶质细胞的功能也越来越受到关注。NG2细胞在人类多种中枢神经系统疾病中扮演重要角色。本文结合最新的研究报道,就其在一些常见的中枢神经系统疾病中的作用进行概括综述。 NG2 cells are a newly discovered group of glial cells widely found in the mature and developing central nervous system. These cells express NG2 chondroitin sulfate proteoglycans and are therefore often referred to as NG2 cells. With the further study of NG2 cell morphology, the function of NG2 glial cells has drawn more and more attention. NG2 cells play an important role in various human diseases of the central nervous system. This article combines the latest research reports, summarizes its role in some common diseases of the central nervous system.