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输注去白细胞血小板或者ABO血型相同的去白细胞血小板,可以减少恶性血液系统疾病患者输注血小板治疗中输血无效和输血反应的发生,改善患者的预后和减少细菌感染的发生。对供体血浆抗原的异源免疫是导致血小板输注无效的重要原因,因此除去血浆上清液可以减少输注反应的发生,然而这一处理将损失大约20%的血小板。目前还没有临床试验比较洗涤和未洗涤血小板在避免出血的有效性和安全性方面的差异。
Infusion of leukocyte platelets or leukocyte platelets of the same ABO blood group can reduce the incidence of transfusions and transfusion reactions in patients with hematologic malignancies who are transfused with platelet transfusions, improve patient outcomes and reduce bacterial infections. Heterologous immunity to donor plasma antigens is a major cause of ineffective platelet transfusions, so removal of plasma supernatant can reduce the incidence of infusion reactions, however, this treatment will lose about 20% of platelets. There are currently no clinical trials comparing the effectiveness and safety of washed and unwashed platelets in avoiding bleeding.