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本文采用镉还原柱层析和比色法测定了20例新生儿败血症患儿外周血亚硝酸／硝酸根离子（NO2－／NO3-）水平，结果新生儿败血症患儿的外周血NO2－／NO3－水平（263．04±300．01μmol／L）显著高于对照组（34．97±13．41μmol／L）（P＜0．05），而且NO2－／NO3-水平与C反应蛋白（CRP）水平和评价病情严重程度的儿科死亡风险（PRISM）评分均显著相关（P＜0．05），认为一氧化氮（NO）与新生儿败血症中的变化及其病情严重程度有关。
In this paper, cadmium reduction column chromatography and colorimetric determination of 20 neonates with sepsis in children with peripheral blood nitrite / nitrate (NO2- / NO3-) levels, the results of neonatal sepsis in children with peripheral blood NO2- / NO3 (263.04 ± 300.01μmol / L) was significantly higher than that of the control group (34.97 ± 13.41μmol / L) (P <0.05), and the levels of NO2- / NO3- and C-reactive protein ) Was significantly correlated with PRISM score (P <0.05). It is believed that nitric oxide (NO) is associated with changes in neonatal sepsis and the severity of the disease.