论文部分内容阅读
作者报告了15例中晚期肺癌经支气管动脉灌注大剂量顺铂(10~150mg)加静脉快速滴注硫代硫酸钠(STS)解毒并行同步放疗的近期疗效观察结果。表明近期有效率CR+PR为93%(14/15),目前全部病例存活。作者认为,大剂量顺铂支气管动脉灌注并同步放疗能明显提高疗效,而使用硫代硫酸钠(STS)解毒和使用基因重组人粒细胞集落刺激因子(rhG-CSF)升白细胞是这种治疗方式得以成功的关键。
The authors reported the short-term results of 15 consecutive patients with advanced lung cancer who were treated with large doses of cisplatin (10 to 150 mg) plus intravenous venous infusion of sodium thiosulfate (STS) detoxification and concurrent radiotherapy. It showed that the recent effective CR+PR was 93% (14/15), and all the current cases survived. The authors believe that high-dose cisplatin bronchial arterial infusion and simultaneous radiotherapy can significantly improve the efficacy, while the use of sodium thiosulfate (STS) detoxification and the use of recombinant human granulocyte colony-stimulating factor (rhG-CSF) is the treatment of leukocytes The key to success.