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目的观察注射用甘利欣联合抗乙肝免疫核糖核酸治疗慢性病毒性乙型肝炎的临床疗效。方法治疗组用甘利欣联合抗乙肝免疫核糖核酸,对照组单用甘利欣,治疗60天,观察治疗效果。结果两组肝功能改善方面无显著差异(P>0.05)。在白蛋白升高率、HBVDNA阴转率、e系统的血清转换率方面有显著性差异,分别为80%、30%、30%、2%、20%、4%,(P<0.05)。结论甘利欣联合抗乙肝免疫核糖治疗慢性乙型病毒肝炎病毒的清除方面明显优于单用甘利欣。
Objective To observe the clinical efficacy of glycopyrrolate injection combined with anti-HBV immune ribonucleic acid in the treatment of chronic viral hepatitis B. Methods The treatment group with Gan Lixin combined anti-hepatitis B immune ribonucleic acid, the control group alone Glycyrrhizin, for 60 days to observe the therapeutic effect. Results There was no significant difference between the two groups in improving liver function (P> 0.05). There were significant differences in albumin rising rate, HBVDNA negative rate and seroconversion rate of e system, which were 80%, 30%, 30%, 2%, 20% and 4% respectively (P <0.05). Conclusion Glycyrrhizin combined with anti-hepatitis B immune ribose treatment of chronic hepatitis B virus clearance was significantly better than the single Gan Lixin.