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目的在结肠癌的治疗中,外科手术是临床通常采用的方法,如传统根治术和完整结肠系膜切除术等。本研究对比分析完整结肠系膜切除术和传统根治术对结肠癌患者近期疗效和预后的影响。方法选取聊城市东昌府人民医院2011-05-01-2013-05-31收治的结肠癌患者80例,其中40例患者接受完整结肠系膜切除术(CME组),40例患者接受传统根治手术(传统组),对两组患者的近期疗效、淋巴结清除数目及复发率进行统计分析。结果 CME组患者的术中出血量、术后肛门排气时间、排便时间和住院时间分别为(115.1±21.4)mL、(3.1±1.0)d、(4.5±1.4)d和(11.8±3.6)d,均优于传统组,差异有统计学意义,均P值<0.05。CME组患者左半结肠淋巴结、右半结肠淋巴结、阳性转移淋巴结和平均淋巴结清除数目分别为(8.2±1.6)、(8.6±1.4)、(18.4±1.1)和(25.7±2.2)个,均优于传统组,差异有统计学意义,均P值<0.05。CME组患者的并发症发生率和复发率均为5.0%(2/40),均显著低于传统组的25.0%(10/40)和22.5%(9/40),差异有统计学意义,P<0.05;CME组患者3年生存率为92.5%(37/40),显著高于传统组的57.5%(23/40),差异有统计学意义,P<0.05。结论完整结肠系膜切除术较传统根治手术治疗结肠癌患者近期疗效好,淋巴结清除数目多,复发率低。
Objectives In the treatment of colon cancer, surgery is commonly used in clinical practice, such as the traditional radical mastectomy and complete resection of mesocolon. This study compared the effects of complete mesorectal excision and conventional radical mastectomy on the short-term outcome and prognosis of patients with colon cancer. Methods To select 80 patients with colon cancer who were treated in Dongchangfu People’s Hospital of Liaocheng 2011-05-01-2013-05-31, 40 patients underwent complete mesorectal excision (CME group) and 40 patients underwent radical operation (Traditional group), the two groups of patients with short-term efficacy, the number of lymph node clearance and recurrence rate of statistical analysis. Results The mean amount of bleeding, postoperative anal exhaust time, defecation time and hospital stay were (115.1 ± 21.4) mL, (3.1 ± 1.0) d, (4.5 ± 1.4) d and (11.8 ± 3.6) d, both were better than the traditional group, the difference was statistically significant, P <0.05. The numbers of left colon, right colon, lymph node and lymph node in the CME group were (8.2 ± 1.6), (8.6 ± 1.4), (18.4 ± 1.1) and (25.7 ± 2.2), respectively In the traditional group, the difference was statistically significant, all P <0.05. The complication rate and recurrence rate in CME group were 5.0% (2/40), which were significantly lower than those in the conventional group (25.0% (10/40) and 22.5% (9/40) respectively) P <0.05. The 3-year survival rate of patients in CME group was 92.5% (37/40), which was significantly higher than 57.5% (23/40) in the conventional group, with a significant difference (P <0.05). Conclusion The complete curative resection of the mesorectal excision is more effective than the traditional radical operation in the treatment of colon cancer. The number of lymph node dissection is large and the recurrence rate is low.