绞股蓝,又名七叶胆(Gynostemma pentaphyllum Makjno),是葫芦科植物,分布于我国南部、朝鲜、日本、印度、东南亚地带。绞股蓝属植物约13种,国产11种,其中以绞股蓝最多。陕西省秦岭以南也有分布。我国绞股蓝的资源极为丰富。开发利用绞股蓝,从天然植物中提取生物活性物质,研制具有独特风味的保健饮料,这是一项具有社会效益和经济效益的科研项目。陕西省药材公司科研室和四川省中药研究所的科研人员,经过一年多时间的合作开发和实验研究,证明我国一些地区绞股蓝中的总皂甙具有与人参皂甙相类似的化学组份与生理活性,且总皂甙的含量还高于日本。在实验的基础上,他们以绞股蓝总皂甙为添加剂,研制成功了具有多种保健作用的可乐型饮料——“古兰可乐”。经过药理实验结果表示,“古兰可乐”原浆能明显提高小鼠中枢神经系统的兴奋性;能显著提高小鼠腹腔巨噬细胞的吞噬功能,表明其能促进免疫功能;小鼠游泳试验表明, Gynostemma pentaphyllum Makjno, also known as Gynostemma pentaphyllum, is a cucurbitaceous plant found in southern China, North Korea, Japan, India, and Southeast Asia. There are about 13 species of Gynostemma and 11 species made in China, among which Gynostemma is the most. There is also distribution south of the Qinling Mountains in Shaanxi Province. China’s Gynostemma is extremely rich in resources. The development and utilization of Gynostemma pentaphyllum, the extraction of biologically active substances from natural plants, and the development of health drinks with unique flavors are scientific research projects with social and economic benefits. After more than one year of collaborative development and experimental research, the scientific research staff of the Shaanxi Provincial Herbal Medicine Company and the Sichuan Provincial Institute of Chinese Materia Medica have proved that total saponins in Gynostemma pentaphyllum in some regions of China have chemical components and physiological activities similar to those of ginsenosides. , and total saponin content is still higher than Japan. Based on the experiments, they used Gynostemma saponins as an additive to develop a cola-style beverage with various health-care effects - “Gurran”. According to the results of pharmacological experiments, the “Guran Kola” puree can significantly increase the excitability of the central nervous system in mice; it can significantly increase the phagocytic function of mouse peritoneal macrophages, indicating that it can promote immune function; mouse swimming test showed ,