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74例男性Ⅱ型糖尿病患者及74例男性正常健康人(对照组)检测了其血骨钙素(BGP)、降钙素(CT)和甲状旁腺素(PTH)。结果表明Ⅱ型糖尿病患者血骨钙素、降钙素水平显著低于对照组(P<0.001)。两组血甲状旁腺素水平无明显差异(P>0.5)。研究表明血骨钙素及降钙素的测定可作为糖 尿病伴代谢性骨病早期诊断的一种指标,推测可能也是糖尿病易发生代谢性骨病的原因之一。
Serum BGP, CTP and PTH were measured in 74 male patients with type 2 diabetes mellitus and 74 healthy male controls (control group). The results showed that the levels of serum osteocalcin and calcitonin in type 2 diabetic patients were significantly lower than those in the control group (P <0.001). There was no significant difference between the two groups in the level of parathyroid hormone (P> 0.5). Studies have shown that the determination of serum osteocalcin and calcitonin can be used as an index for the early diagnosis of diabetic with metabolic bone disease, speculated that diabetes may be one of the causes of metabolic bone disease.