检则大输液热原的经典方法是采用家兔法。80年代后，国内一些单位试用鲎试验法检测大输液热原[1]，1988年，国家部颁标准规定，鲎试验法可用于注射用水、0．9％氯化钠注射液、5％葡萄糖注射液、10％葡萄糖注射液4种大输液细菌内毒素的检查，若检测不合格，还必须用家兔法检测。 Check the infusion of pyrogen is the classic method of rabbit law. After the 1980s, some units in China tried to test the large hydrothermal pyrogen test [1]. In 1988, the national ministerial standards stipulated that the test method can be used for injection of water, 0.9% sodium chloride injection, 5% glucose Injection, 10% glucose injection of four large transfusion bacterial endotoxin test, if the test failed, but also must be detected by rabbit method.