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我们曾观察到腹腔和皮下注射巩县黄腐酸(以下简称FA)对消炎痛引起的大鼠胃粘膜损伤有明显的预防作用。本工作观察口服巩县FA对消炎痛引起的胃损伤是否有预防作用。给禁食24小时的大鼠皮下注射消炎痛20mg/kg,四小时后观察胃粘膜损伤。
We have observed that intraperitoneal and subcutaneous injection of Gongxian fulvic acid (hereinafter referred to as FA) on indomethacin-induced rat gastric mucosal injury has a significant preventive effect. This work observed oral Gongxian FA indomethacin-induced gastric injury if there is a preventive effect. Rats, fasted for 24 hours, were injected subcutaneously with indomethacin 20 mg / kg and gastric mucosal damage was observed after four hours.