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作者对70例可疑肿瘤病人的胸腔积液和血清进行肿瘤标记物的检测,同时对胸液作常规细胞学检查,以探讨肿瘤标记物对恶性胸液的诊断价值。肿瘤标记物包括6-磷酸已糖异构酶、乳酸脱氢酶、糖蛋白、β2微球蛋白、铁蛋白,总唾液酸、甲胎蛋白、癌胚抗原(CEA),人类绒毛膜促性腺激素(β-HCG)、IgE 等。胸液和血标本要在同一天收集,离心后放于-20℃保存,存放时间不得超讨2个月。结果分析70例胸腔积液病人经细胞学、活检或尸检诊断为恶性肿瘤者41例(1组),其中肺癌19例,间皮瘤7例,卵巢癌4例,乳腺癌3例,混合癌8例.细菌性感染所致胸液(2组)22例。由肝病或心
The authors detected pleural effusions and serum from 70 patients with suspected tumors and performed routine cytological examinations of the pleural effusions to investigate the diagnostic value of tumor markers for malignant pleural fluid. Tumor markers include 6-phosphohexose isomerase, lactate dehydrogenase, glycoprotein, β2 microglobulin, ferritin, total sialic acid, alpha-fetoprotein, carcinoembryonic antigen (CEA), human chorionic gonadotropin (β-HCG), IgE, etc. The pleural fluid and blood specimens should be collected on the same day, stored at -20°C after centrifugation, and stored for no more than 2 months. RESULTS: Forty patients with pleural effusions who were diagnosed as malignant by cytology, biopsy or autopsy were analyzed in 41 patients (group 1). Among them, 19 were lung cancer, 7 were mesothelioma, 4 were ovarian cancer, 3 were breast cancer, mixed cancer. 8 cases. 22 cases of pleural fluid caused by bacterial infection (2 groups). From liver disease or heart