目的:探讨早发型重度子痫前期对围生期母婴预后的影响及保守治疗的适宜时间。方法:对161例早发型重度子痫前期病例进行分析,根据其发病孕周分为3组,即A组(孕周<28周),B组(28孕周≤孕周<32孕周),C组(32孕周≤孕周<34孕周)。观察发病情况、病情特点及母婴并发症。结果:早发型重度子痫前期3组患者并发症发生率无统计学意义;发病孕周越早,胎儿窘迫、新生儿死亡率及围生儿死亡率越高,3组间差异均有统计学意义(P<0.05);各组患者的分娩方式均以剖宫产为主。结论:早发型重度子痫前期有较高的母婴并发症,在期待治疗过程中,应严密监护母婴情况,适时终止妊娠,终止妊娠方式首选剖宫产。 Objective: To investigate the effect of early-onset severe preeclampsia on the prognosis of perinatal maternal and infant and the appropriate time for conservative treatment. Methods: One hundred and sixty-one cases of early-onset severe preeclampsia were divided into three groups according to their gestational age: group A (gestational age <28 weeks), group B (gestational age ≤28 weeks <32 gestational weeks) , Group C (32 gestational weeks ≤ gestational age <34 gestational weeks). Observed the incidence of disease characteristics and maternal and child complications. Results: The incidence of complications in early-onset severe preeclampsia patients was not statistically significant. The earlier the gestational age was, the higher the fetal distress, neonatal mortality and perinatal mortality were. The differences among the three groups were statistically significant Significance (P <0.05). The cesarean section was the main mode of delivery in each group. Conclusion: Early onset severe preeclampsia has higher maternal and infant complications. In the course of waiting for treatment, maternal and infant conditions should be closely monitored, pregnancy termination should be timely, and cesarean section should be terminated by the first trimester.