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目的观察和评价微卡(注射用母牛分枝杆菌菌苗)对预防煤工尘肺(CWP)肺结核复发的疗效。方法采用随机配对分组法将67例临床治愈CWP肺结核患者分成预防组32例和对照组35例,预防组临床治愈后每年的1～3月,共3个月,每2周作臀部肌内深部注射微卡针22.5μg/次,共4年。对照组临床治愈后仅随访观察。结果 4年后预防组32例有1例复发,对照组35例有7例复发,2组复发比较,差异有统计学意义(P<0.05) 微卡在预防CWP肺结核复发方面有一定的疗效。
Objective To observe and evaluate the effect of micro-card (Mycobacterium vaccae injection) on the prevention of CWP pulmonary tuberculosis recurrence. Methods A total of 67 cases of CWP-treated patients with CWP were divided into two groups: prevention group (32 cases) and control group (35 cases). The preventive group received 1 ~ 3 months a year after clinical cure, Micro-needle 22.5μg / time, a total of 4 years. The control group only follow-up after clinical cure. Results In 4 years, there were 1 case relapse in 32 cases of prevention group, 7 cases relapse in 35 cases of control group and 2 cases relapse. The difference was statistically significant (P <0.05). Micro-card had some curative effect in preventing relapse of CWP tuberculosis.