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目的 :考察尿激酶、链激酶和阿替普酶治疗急性心肌梗死溶栓疗法的经济效果。方法 :将 15 1例急性心肌梗死病人随机分为 3组 ,运用成本 效果分析方法进行评价。结果 :尿激酶、链激酶和阿替普酶治疗急性心肌梗死的 3组治疗方案治疗效果基本相同 (P >0 .0 5 ) ,治疗费用相差却十分显著 ,尿激酶方案的成本 效果比最好 ,为最佳治疗方案。结论 :药物经济学方法在优化治疗方案、提高经济效益方面有重要作用。
OBJECTIVE: To investigate the economic effects of urokinase, streptokinase and alteplase in thrombolytic therapy of acute myocardial infarction. Methods: A total of 151 acute myocardial infarction patients were randomly divided into three groups and evaluated by cost-effectiveness analysis. Results: The three groups of treatment regimen of urokinase, streptokinase and alteplase for acute myocardial infarction had the same treatment effect (P> 0.05), but the cost difference was very significant. The cost-effectiveness of the urokinase program was the best , For the best treatment. Conclusion: The pharmacoeconomic methods play an important role in optimizing treatment options and increasing economic benefits.