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钙离子流入阻滞剂主要阻滞Ca~(++)(钙离子)流入细胞,并不对抗Ca~(++)在细胞内的动能,对细胞内Ca~(++)释放的作用也很轻微,故而得名。近十余年,这类药物已用于治疗高血压、心绞痛、肥厚性心肌病、心律失常等,引起了广泛重视。现将其主要作用机制和主要制剂的临床应用简介如下。
The calcium influx blockers mainly block the influx of Ca ~ (++) (calcium ions) into the cells and do not antagonize the kinetic energy of Ca ~ (++) in the cells and the effect on intracellular Ca ~ (++) release Very slight, so named. Nearly ten years, these drugs have been used to treat hypertension, angina, hypertrophic cardiomyopathy, arrhythmia, aroused widespread attention. Now its main mechanism of action and clinical application of the main preparations are as follows.