论文部分内容阅读
白血病细胞对化疗耐药是当前成功治疗白血病的 主要障碍之一，细胞耐药存在多种机制，近年来较多学 者将研究的重点放在了细胞凋亡的抑制剂上。在诸多 细胞凋亡的“抑制剂”中最引人注目的是 Bcl-2基因，它 是用以研究细胞凋亡抑制的最佳模型，它的表达状态 在一定程度上决定肿瘤的发生、发展及癌细胞对化疗
Leukemia cell resistance to chemotherapy is one of the main obstacles in the successful treatment of leukemia. There are many mechanisms of drug resistance in cells. In recent years, more scholars have focused their research on inhibitors of apoptosis. Among the many “inhibitors” of apoptosis, the Bcl-2 gene is the most attractive one. It is the best model to study the inhibition of apoptosis, and its expression state to a certain extent determines the occurrence and development of tumors And cancer cells on chemotherapy