手术本身使病人对肿瘤生长的阻力降低，Kodama还证实手术应激确可增加肿瘤转移的倾向，机械性捣动原发肿瘤也可发生血源性肿瘤栓子，所谓种植将产生继发性肿瘤生长，在鼠实验中早在手术后1小时就可见肿瘤栓子。设想腹腔镜手术对免疫抑制较轻，自发性肿瘤转移可能更少些。进行初 The operation itself has reduced the patient’s resistance to tumor growth. Kodama also confirmed that surgical stress can increase the tendency of tumor metastasis. Mechanically inspiratory primary tumors can also produce blood-borne tumor emboli. The so-called implantation will produce secondary tumors. Growth, tumor emboli were visible as early as 1 hour after surgery in the mouse experiment. It is envisaged that laparoscopic surgery is less immunosuppressive and spontaneous tumor metastasis may be less. At the beginning