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1984~1986年在四川省的18市地州100~207所医院进行了连续三年的出生缺陷监测。共监测围产儿295 484例。其中3 655例有出生缺陷。本文报告无脑儿、脊柱裂、脑膨出、脑积水、小耳、腭裂,伴有或不伴有腭裂的唇裂、食道闭锁或狭窄,直肠肛门闭锁或狭窄、尿道下裂、肢体短缩畸形、脐膨出和膈疝等13种出生缺陷逐年的发生率及其在城乡男女间的分布。全省出生缺陷平均总发生率为123.70/万。唇腭裂发生率居第1位(20.20/万),神经管缺陷居第2位(14.15/万)。神经管缺陷,脑积水和肢体短缩畸形在城乡间发生率差异有显著性(P<0.01)。神经管缺陷、小耳、直肠肛门闭锁或狭窄和尿道下裂在男女间发生率差异有显著性(P<0.01)。
From 1984 to 1986, 100 consecutive birth defects were monitored in 100 to 207 hospitals in 18 prefectures of Sichuan Province. A total of 295,484 perinatal children were monitored. Of these, 3 655 had a birth defect. This article reports no brain, spina bifida, encephalocele, hydrocephalus, small ears, cleft palate, cleft lip with or without cleft palate, esophageal atresia or stenosis, rectal anal atresia or stenosis, hypospadias, limb shortening deformity , Umbilical swelling and diaphragmatic hernia and other 13 kinds of birth defects year by year incidence and distribution in urban and rural areas between men and women. The overall average incidence of birth defects in the province was 123.70 / million. Cleft lip and palate occurred in the first place (20.20 / million), the second place of neural tube defects (14.15 / million). There was a significant difference in the incidence of neural tube defects, hydrocephalus and limb shortening between urban and rural areas (P <0.01). The incidence of neural tube defects, small ears, anorectal atresia or stenosis and hypospadias was significantly different between men and women (P <0.01).