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无环鸟苷(Acyclorir.ACV)系一选择性抗单纯疱疹病毒(HSV)药物,具有作用强,毒副作用小的优点。眼科配成滴眼液点眼用于治疗各型HSV角膜炎取得良好效果。本文用[~3H]—ACV配成滴眼液(0.1%)给家兔点眼,观察其眼内透性并进行药代动力学分析。
Acyclorir (ACV) is a selective anti-herpes simplex virus (HSV) drug, with the advantages of strong side effects. Eye drops with eye drops for the treatment of various types of HSV keratitis achieved good results. In this paper, [~ 3H] -ACV eye drops (0.1%) were given to the eyes of rabbits to observe the intraocular permeability and pharmacokinetic analysis.