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目的分析ICU危重患者持续镇静治疗的临床效果。方法将该院ICU收治的300例危重患者随机分为丙泊酚组和咪唑地西泮组,各150例,两组患者分别采用丙泊酚联合芬太尼及咪唑地西泮联合芬太尼进行镇静治疗,对两组患者治疗效果进行比较和分析。结果两组患者镇静前后血糖、血清皮质醇、促肾上腺皮质激素及胃液p H值的比较具有明显差异(P<0.05)。丙泊酚组评分为3~5分的患者有137例,占91.33%;咪唑地西泮组评分为3~5分的患者有135例,占90.00%;组间比较差异无统计学意义(P>0.05)。结论采用丙泊酚或咪唑地西泮对ICU危重患者给予镇静治疗,可有效减少患者额的应激反应,有利于危急情况的预防,可帮助患者轻松、安全度过危险期,值得推广使用。
Objective To analyze the clinical effect of continuous sedation in critically ill patients with ICU. Methods 300 critically ill patients admitted to ICU of the hospital were randomly divided into propofol group and midazolam group, with 150 cases in each group. Patients in both groups were treated with propofol combined with fentanyl and midazolam combined with fentanyl Sedative treatment, the treatment effect of two groups were compared and analyzed. Results Before and after sedation, the blood glucose, serum cortisol, adrenocorticotropic hormone and p H in gastric juice had significant difference (P <0.05). In the propofol group, there were 137 patients (91.33%) with a score of 3 to 5, and 135 patients (90.00%) with a score of 3 to 5 in the imidazofam group. There was no significant difference between the two groups P> 0.05). Conclusions Propofol or midazolam can be used to sedative therapy in critically ill patients with ICU, which can effectively reduce the amount of stress response in patients and prevent the emergency. It can help patients easily and safely pass the dangerous period and is worth popularizing.