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目的对比分析胸腹水沉淀物琼脂包裹-石蜡包埋(APSM)切片与液基薄层(TCT)涂片细胞检查结果,探讨其临床诊断意义。方法对长葛市人民医院2012年1月至2013年3月诊治的86例胸腹水病例资料进行回顾性分析,所有患者的APSM切片与TCT涂片细胞检查及活检组织切片结果资料齐全,将前两者与活检组织切片结果进行对比,比较APSM切片与TCT涂片的判断结果。结果 APSM切片制片成功率为87.8%(86/98),明显低于TCT涂片的98.9%(86/87),差异有统计学意义(P<0.05);与活检组织切片结果对照,APSM切片的诊断正确率为96.5%(83/86),TCT涂片的诊断正确率为94.2%(81/86),差异无统计学意义(P>0.05);APSM组对恶性肿瘤细胞学分型准确率为94.9%(37/39),明显高于TCT组的76.9%(30/39),差异有统计学意义(P<0.05)。结论胸腹水APSM切片与TCT涂片细胞检查准确性均较高,TCT涂片制片成功率高、APSM切片对恶性肿瘤分型价值高,临床上应综合应用两种检查方案提高疾病诊断正确率。
OBJECTIVE: To compare the results of smear-cell smears of pleural effusion aspergillosis sediment agar-encapsulated paraffin-embedded (APSM) sections and liquid-based thin layer (TCT) smears, and to explore its clinical significance. Methods The data of 86 cases of pleural and ascites patients diagnosed and treated in Changge People’s Hospital from January 2012 to March 2013 were retrospectively analyzed. All the data of APSM section, TCT smear cell test and biopsy section were complete. The results of biopsy and biopsy were compared to compare the results of APSM and TCT smears. Results The success rate of APSM slice preparation was 87.8% (86/98), which was significantly lower than that of TCT smears (98.9%, 86/87) (P <0.05). Compared with biopsies, APSM The diagnostic accuracy rate of slices was 96.5% (83/86), and the diagnostic accuracy rate of TCT smears was 94.2% (81/86), with no significant difference (P> 0.05). The APSM group had accurate cytological typing The rate was 94.9% (37/39), which was significantly higher than that of TCT group (76.9%, 30/39). The difference was statistically significant (P <0.05). Conclusion APSM sections of pleural and ascitic fluid and TCT smear cells have higher accuracy. The success rate of TCT smear preparation is high. APSM sections are of high value in malignant tumor classification. Two kinds of examination schemes should be combined to improve the accuracy of disease diagnosis .