作者采用腹腔注射专一性肝毒性药物——D-氨基半乳糖(GalN)于Wistar雄性大鼠复制暴发性肝衰型肝性脑病模型,用放射受体分析法动态测定了血中GABA浓度变化,并用生大黄煎液灌胃治疗肝衰动物。实验结果表明;肝衰组动物,在GalN注射后,随病情加重,血中GABA随之增高,二者呈平行关系 The authors used intraperitoneal injection of a specific hepatotoxic drug, D-galactosamine (GalN), to replicate a model of fulminant hepatic hepatic encephalopathy in Wistar male rats and to dynamically measure changes in blood GABA concentration using radioreceptor assays. , and the treatment of hepatic failure animals with rhubarb decoction. The experimental results showed that in the liver failure group, after the GalN injection, GABA increased in the blood as the condition worsened, and the two were in a parallel relationship.