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目的 :讨论肾移植术后并发霉菌感染的诊断与治疗。方法 :本组 2 1例患者 ,诊断采用 3～ 5次血、尿培养、痰涂片 ,结合主要临床表现 ;治疗采用全身支持疗法 ,同时调整激素用量 ,减少或停用强效抗生素 ,5 %苏打水漱口 ,二性霉素B、制霉菌素、里素劳单用或联合应用。结果 :治愈 18例 ,死亡 3例。结论 :对肾移植术后患者 ,无法解释的持续性发热、肺部感染而X线胸片无异常者 ,应反复作痰涂片 ,血、尿培养 ,结合临床主要症状作出正确诊断。术后预防感染时 ,非必要情况下 ,应尽量首选窄谱抗生素减少强效抗生素的用量及时间 ,从而预防或减少霉菌感染。对已感染霉菌者可单用或联合应用二性霉素B、里素劳
Objective: To discuss the diagnosis and treatment of fungal infection after kidney transplantation. Methods: Twenty-one patients in our hospital were diagnosed with blood and urine culture and sputum smear and combined with the main clinical manifestations. The patients were treated with systemic supportive therapy while adjusting the dosage of hormones to reduce or stop the use of potent antibiotics. The 5% Soda water mouthwash, amphotericin B, nystatin, in the labor alone or in combination. Results: 18 cases were cured and 3 died. CONCLUSION: For patients after renal transplantation, unexplained persistent fever and pulmonary infection without abnormalities of X-ray, should be repeated sputum smear, blood and urine culture, combined with the main clinical symptoms to make the correct diagnosis. Postoperative infection prevention, non-essential circumstances, should be the first choice of narrow-spectrum antibiotics to reduce the amount of potent antibiotics and time, thereby preventing or reducing fungal infections. For those who have been infected with mold can be used alone or in combination with amphotericin B, where vegetarian