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1950年Barrett 氏首先描述了食管远端正常鳞状上皮被柱状上皮所取代现象。目前大多数研究者据信本症是伴有慢性返流性食管炎的一种获得性状况。本病诊断的组织学标准是在管状食管内和下食管括约肌近端,出现柱状上皮及具胃和小肠上皮细胞特征的各类细胞。文内19例中,男15例,女4例。年龄24～75岁。透视下最常见到的征象是胃—食管返流和滑动性裂孔疝,食管狭窄11例,波及食管大部和中段下段各1例,中段狭窄3例,下段狭窄6例。10例有不同程度食管炎。1例食管正常,2例仅有食管返
In 1950 Barrett first described the phenomenon that the distal esophageal normal squamous epithelium was replaced by columnar epithelium. At present, most researchers believe that this disease is an acquired condition with chronic reflux esophagitis. The histological criteria for the diagnosis of this disease are in the tubular esophagus and in the proximal part of the lower esophageal sphincter, where columnar epithelium and various types of cells characterized by gastric and intestinal epithelial cells appear. Among 19 cases in the literature, 15 were males and 4 were females. Age 24-75 years old. The most common signs under fluoroscopy were gastroesophageal reflux and sliding hernia, 11 cases of esophageal stenosis, 1 case in the lower part of the esophagus and the middle segment, 3 cases of middle stenosis, and 6 cases of lower stenosis. 10 cases had different degrees of esophagitis. 1 case of normal esophagus, 2 cases only with esophageal return