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目的探讨甘露醇治疗脑卒中过程中对肾脏的损害。方法对我院40例脑卒中患者因应用甘露醇致急性肾损伤临床回顾性分析。结果 40例患者应用甘露醇后,蛋白尿19例,血尿15例,管型尿10例,血肌酐超过正常范围25例,经停用甘露醇,采用其他降颅压药物、对症治疗及血液透析等,肾功能恢复正常36例,死亡3例,自动出院1例。结论脑卒中治疗过程中应用甘露醇可致急性肾损伤。
Objective To investigate the effect of mannitol on the kidney during stroke. Methods A retrospective analysis of 40 patients with stroke in our hospital due to mannitol-induced acute kidney injury. Results After the application of mannitol in 40 patients, 19 cases of proteinuria, 15 cases of hematuria, 10 cases of tubular urine and 25 cases of serum creatinine exceeded the normal range. After mannitol was stopped and other intracranial pressure drugs were used, symptomatic treatment and hemodialysis And so on, 36 cases of normal renal function returned to normal, 3 died, 1 case was discharged automatically. Conclusion The application of mannitol during stroke treatment can cause acute renal injury.