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目的分析对比高血压合并冠心病患者使用氨氯地平阿托伐他汀钙片治疗的临床效果及表现。方法将在我院确诊的高血压合并冠心病60患者随机分为两组,观察组和对照组各30人。对照组口服氨氯地平片治疗,观察组口服氨氯地平阿托伐他汀钙片治疗,分析对比两组患者的治疗效果及不良反应。结果观察组患者治疗前平均收缩压为(154±4)mm Hg,平均舒张压为(96±4)mm Hg,治疗后平均收缩压为(126±6)mm Hg,平均舒张压为70±8mm Hg。对照组患者治疗前平均收缩压为(159±4)mm Hg,平均舒张压为(137±80mm Hg,治疗后平均收缩压为93±6mm Hg,平均舒张压为(71±4)mm Hg。两组患者治疗前后的血压情况均有降低,但观察组的降低程度明显大于对照组,两组患者治疗前后的血脂情况均有降低,但观察组的降低程度明显大于对照组,两组患者治疗效果及前后对比具有统计学差异(P<0.05)。结论氨氯地平阿托伐他汀对于高血压合并冠心病病人的临床症状有明显的改善作用,并且效果显著,不良反应较低。
Objective To analyze the clinical effects and manifestations of patients treated with amlodipine atorvastatin calcium in hypertensive patients with coronary heart disease. Methods Sixty patients with hypertension and coronary heart disease diagnosed in our hospital were randomly divided into two groups, 30 in observation group and control group. Control group oral amlodipine treatment, the observation group oral amlodipine atorvastatin calcium treatment, analysis and treatment of two groups of patients compared the efficacy and adverse reactions. Results Before treatment, the average systolic blood pressure was (154 ± 4) mm Hg and the average diastolic blood pressure was (96 ± 4) mm Hg. The average systolic blood pressure was (126 ± 6) mm Hg and the mean diastolic blood pressure was 70 ± 8mm Hg. The control group had mean systolic blood pressure (159 ± 4) mm Hg and mean diastolic pressure (137 ± 80 mm Hg) after treatment, with an average systolic pressure of 93 ± 6 mm Hg and an average diastolic pressure of (71 ± 4) mm Hg after treatment. Before and after treatment, blood pressure decreased in both groups, but the reduction in the observation group was significantly greater than that in the control group. Both groups had decreased blood lipid levels before and after treatment, but the reduction in the observation group was significantly greater than that in the control group (P <0.05) .Conclusion Amlodipine atorvastatin can improve the clinical symptoms of patients with hypertension and coronary heart disease, and the effect is remarkable and the adverse reaction is low.