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1 利尿剂 1.1 噻嗪类:这类的利尿剂,包括氯噻嗪、双氢克尿塞,是一种芳香的磺胺制剂。这两种药物有密切联系的化学式。于是被局部应用磺胺引起过敏的病人。如果全身服用,可以发生湿疹性皮疹。他们还具有强有力的感光作用。有人指出,4—氯—2—羟基苯甲酸—N—n—丁基酰胺和各种磺胺衍化物(包括氯噻嗪和双氢克尿素)之间有交叉敏感生。有文献报告:运用双氢克尿塞,在日光曝晒到的暴露部位出现湿疹样皮疹的病
A diuretic 1.1 Thiazides: This type of diuretic, including chlorothiazide, hydrochlorothiazide, is an aromatic sulfonamide preparation. The two drugs are closely related to the chemical formula. So the local application of sulfonamide cause allergy patients. If taken orally, eczematous rashes can occur. They also have a strong photographic effect. It was pointed out that there is a cross sensitivity between 4-chloro-2-hydroxybenzoic acid-N-n-butylamide and various sulfonamide derivatives, including chlorothiazide and diazocin. There are reports of the use of hydrochlorothiazide, eczema-like rash on exposed areas exposed to sunlight