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目的方法:T_2N_oM_o期乳腺癌5年生存率达80%以上,预后比较好,但仍有少数患者短期内因复发死亡。本文对5年内死亡及生存超过5年的病例进行回顾性研究,对两组患者肿瘤大小,组织学类型、组织学分级、核分级、肿瘤局部脉管侵犯情况、有无淋巴结转移及数目、雌激素受体(ER)测定、是否正规辅助治疗8个指标进行对照分析。结果:组织学分级、核分级、肿瘤内脉管有无侵犯,雌激素受体情况二组有显著性差异。结论:对于T_2N_oN_o期患者,组织学分级、核分级是判断预后和术后化疗的可靠指标,ER及脉管侵犯情况可作为重要的参考指标。
Objective method: The 5-year survival rate of T_2N_oM_o breast cancer is more than 80%, and the prognosis is better. However, there are still a few patients who died due to recurrence in the short term. This article reviews retrospectively the cases that died and survived more than 5 years in 5 years. The tumor size, histological type, histological grade, nuclear grade, tumor vascular invasion, lymph node metastasis and number, and female were compared between the two groups. Hormone receptor (ER) assays and formal adjuvant therapy were used for comparative analysis. RESULTS: Histological grade, nuclear grade, presence or absence of tumor invasion, and estrogen receptor status were significantly different in the two groups. Conclusion: For T_2N_oN_o patients, histological grade and nuclear grade are reliable indicators for prognosis and postoperative chemotherapy. ER and vascular invasion can be used as important reference indicators.