经前期综合征极常见,其社会发病率很高,约有80％的妇女有此等症状,其中30％有体力或精神方面暂时性衰退。此症虽常见,但其病理生理至今未明,且大多数治疗均令人失望。对其病理生理,有些假说从末稍机理方面作阐明:认为可能系雌-孕激素平衡失调,但既不存在雌-孕激素平衡的失调,而用孕激素治疗又无效,故此假说不能成立。也有解释为继发性醛固酮增多症、低血糖或变态反应,但这些假说亦有待于证实。目前认为系前列腺素,尤其是子宫内膜释放的前列腺素作用,虽然其引起本症的原因尚未确知,但已证实有降 Premenstrual syndrome is extremely common, its social incidence is very high, about 80% of women have these symptoms, of which 30% have a temporary physical or mental decline. Although this disease is common, but its pathophysiology is unknown, and most of the treatment are disappointing. Some of its pathophysiology of the hypothesis from the last mechanism to clarify: that may be estrogen-progesterone balance disorders, but neither the progesterone balance imbalance, and treatment with progesterone and ineffective, so the hypothesis can not be established. There are also explanations for secondary hyperaldosteronism, hypoglycemia or allergic reactions, but these hypotheses also need to be confirmed. Now that prostaglandins prostaglandins, especially endometrial release of prostaglandin role, although the cause of the disease is not yet known, but it has been confirmed with a drop