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目的探讨血清肿瘤标志物癌胚抗原(CEA)、糖类抗原CA19-9、CA125、CA50、恶性肿瘤相关因子(TSGF)联合检测在胰腺癌诊断中的应用价值。方法 120例胰腺癌患者(胰腺癌组)、70例胰腺良性疾病患者(胰腺良性疾病组)、80例健康人(健康对照组),检测三组血清中CEA、CA19-9、CA125、CA50、TSGF水平。结果联合测定CEA、CA19-9、CA125、CA50、TSGF敏感度为91.6%。结论 5种肿瘤标志物联合检测可提高胰腺癌诊断的敏感度和准确度。
Objective To investigate the value of combined detection of serum tumor markers carcinoembryonic antigen (CEA), carbohydrate antigens CA19-9, CA125, CA50 and malignant tumor related factor (TSGF) in the diagnosis of pancreatic cancer. Methods 120 patients with pancreatic cancer (pancreatic cancer group), 70 patients with benign pancreatic disease (benign pancreatic disease group) and 80 healthy people (healthy control group) were enrolled in this study. Serum levels of CEA, CA19-9, CA125, CA50, TSGF level. Results The sensitivity of combined detection of CEA, CA19-9, CA125, CA50 and TSGF was 91.6%. Conclusion The combined detection of 5 tumor markers can improve the sensitivity and accuracy of diagnosis of pancreatic cancer.