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目的:探讨影响婴儿捂热综合征(IMS)预后的相关因素。方法:回顾性调查我院重症监护病房(ICU)近5年收治住院的51例IMS患儿资料,进行单因素χ2检验,再对差异有统计学意义的单因素进行多因素Logistic回归分析。结果:51例IMS患儿中,9例死亡,病死率17.6%。IMS患儿死亡组与存活组之间比较,年龄和性别差异无统计学意义(P>0.05),捂热时长、体温、改良Glasgow昏迷评分(PCIS)、小儿危重病例评分(GCS)、脏器功能障碍数目、pH、乳酸、血浆渗透压、Na+浓度、Ca2+浓度、血糖、白蛋白、肌酸激酶同工酶、脑利钠肽、D-二聚体差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,PCIS≤70分、GCS≤8分、脏器功能障碍数目≥3、血Na+≥150 mmol/L、D-二聚体≥2 mg/L为影响IMS患儿预后的独立危险因素。结论:临床医护人员需充分认识影响IMS患儿预后的危险因素,以期早期识别、合理治疗IMS,降低病死率和改善预后。
Objective: To explore the factors influencing the prognosis of infantile warm-hot syndrome (IMS). Methods: The data of 51 IMS children admitted to ICU in our hospital for 5 years were retrospectively analyzed. The single factor χ2 test was used to analyze the univariate logistic regression analysis. Results: Among 51 IMS children, 9 died and the case fatality rate was 17.6%. There was no significant difference in age and gender between IMS group and survivorship group (P> 0.05). The length of time, body temperature, modified Glasgow Coma Scale (PCIS), pediatric critical illness score (GCS) There were significant differences in the number of dysfunction, pH, lactic acid, plasma osmolality, Na + concentration, Ca2 + concentration, blood glucose, albumin, creatine kinase isoenzyme, brain natriuretic peptide and D-dimer . Multivariate logistic regression analysis showed that PCIS≤70 points, GCS≤8 points, organ dysfunction number≥3, blood Na +≥150 mmol / L, D-dimer≥2 mg / L were the prognostic factors in children with IMS Independent risk factors. Conclusion: Clinicians need to fully understand the risk factors influencing the prognosis of children with IMS in order to identify early, treat IMS reasonably, reduce mortality and improve prognosis.