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目的探讨对足月妊娠胎膜早破产妇施行临床干预,试图减少产妇的绒毛羊膜炎和新生儿并发症的发病率,为围产期合理的治疗、并发症的预防提供理论基础。方法本研究对我院2005年1月~2008年12月期间住院足月分娩产妇1 886例中胎膜早破、孕龄37~42周、年龄24~32岁、头先露的156例及时进行临床干预,作为实验组,随机抽取2001年1月~2004年12月1 981例中足月胎膜早破、孕龄≥37周、头先露的未加任何干预的156例作为对照组。所获数据进行χ2检验。结果2组产妇绒毛羊膜炎发生率,实验组与对照组相比明显降低(P<0.05)。2组新生儿情况比较,实验组新生儿窒息率、新生儿肺炎发生率降低(P<0.05)。实验组与对照组分娩方式比较,由于实施计划分娩,实验组剖宫产率降低(P<0.01)。结论足月妊娠胎膜早破的孕妇,尽早进行计划分娩,预防性的应用抗生素等临床干预措施,能有意义的减少产妇绒毛羊膜炎以及新生儿窒息率、肺炎发生率。
Objective To investigate the clinical intervention of premature rupture of membranes for full-term pregnant women in order to reduce the incidence of chorioamnionitis and neonatal complications in maternal and provide a theoretical basis for rational treatment of perinatal complications and prevention of complications. Methods This study of our hospital from January 2005 to December 2008 period of hospital delivery of 1 886 cases of full-term premature rupture of membranes in children, gestational age 37 to 42 weeks, aged 24 to 32 years, first-exposed first 156 cases of timely As the experimental group, randomly selected from January 2001 to December 2004 in 1 981 cases of full-term premature rupture of membranes, gestational age ≥ 37 weeks, the first exposed without any intervention in 156 cases as a control group . The data obtained for χ2 test. Results The incidence of chorioamnionitis in the two groups was significantly lower than that in the control group (P <0.05). The incidence of neonatal asphyxia and neonatal pneumonia in the experimental group was significantly lower than that in the neonatal group (P <0.05). Compared with the mode of delivery in experimental group and control group, the cesarean section rate in the experimental group decreased due to planned delivery (P <0.01). Conclusions Pregnant women with full-term premature rupture of membranes, as planned early delivery, preventive use of antibiotics and other clinical interventions, can significantly reduce maternal chorioamnionitis and neonatal asphyxia and pneumonia incidence.