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目的探讨肥厚型心肌病患者出现晕厥等严重症状的预测因素。方法分析52例肥厚型心肌病患者多项检查的表现特征,按照有无晕厥的临床症状分成两组,进行对照分析。结果晕厥组有多项指标较非晕厥组有显著增加,包括QT间期延长(456±20msvs421±21ms,p<0.05);左室流出道梗阻(61.5%vs5.1%,p<0.05),心前区收缩期3/6以上的杂音(92.3%vs25.6%,p<0.05)。左室壁厚度≥23mm(38.4%vs5.1%,p<0.05)。结论(1)QT间期延长,(2)左室流出道梗阻,(3)心前区3/6以上的收缩期杂音;(4)左室壁厚度≥23mm是肥厚型心肌病患者发生晕厥等严重症状的预测因素。
Objective To investigate the predictors of severe symptoms such as syncope in patients with hypertrophic cardiomyopathy. Methods Fifty-two patients with hypertrophic cardiomyopathy were examined for the characteristics of multiple examinations, and were divided into two groups according to the clinical symptoms of syncope or not. Results The number of syncope group increased significantly (P <0.05). The QT interval prolonged (456 ± 20 ms vs 421 ± 21 ms, p <0.05) Premorbid systolic 3/6 murmurs (92.3% vs 25.6%, p <0.05). Left ventricular wall thickness ≥ 23 mm (38.4% vs 5.1%, p <0.05). Conclusions (1) QT interval prolongation, (2) left ventricular outflow tract obstruction, (3) precardial more than 3/6 systolic murmur, (4) left ventricular wall thickness of 23mm is hypertrophic cardiomyopathy in patients with syncope And other serious symptoms of predictors.