近年美国耐氨苄青霉素痢疾杆菌菌株日益增加,此种耐药株通常亦耐四环素族、磺胺类和氯霉素。试管内痢疾杆菌虽对呋喃唑酮、头孢菌素、萘啶酸和庆大霉素敏感,但临床试验证明,口服呋喃唑酮和头孢菌素Ⅲ的疗效与安慰剂相似,原因是血清中药物浓度极低测不出来。庆大霉素尚缺乏对照临床试验。作者对227株痢疾杆菌药敏试验发现,虽然其中56％菌株对 In recent years, the United States resistant to ampicillin dysentery bacilli strains increasing, such resistant strains are usually also resistant tetracycline, sulfonamides and chloramphenicol. Although in vitro test tube dysentery bacilli furazolidone, cephalosporins, nalidixic acid and gentamicin sensitive, but clinical trials show that the efficacy of oral furazolidone and cephalosporin III and placebo similar to the low serum concentration of the drug Not come out. Gentamicin is still lacking in controlled clinical trials. The author of 227 dysentery bacilli drug susceptibility test found that although 56% strains of them