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目的:了解SEN病毒D/H亚型在不同肝炎患者和献血员中的感染情况。方法:采用巢式聚合酶链反应对收集的健康献血者和各型肝炎患者进行SENV-D亚型和H亚型DNA检测。结果:无偿献血者中SENV-D的感染率为25.9%,SENV-H为24.4%;急性甲肝患者中SENV-D的感染率为14.5%,SENV-H为32.7%;慢性乙肝患者中SENV-D的感染率为46%,SENV-H为45.2%;在丙肝患者中SENV-D和SENV-H的感染率均为65%;在非甲-非戊型肝炎患者中SENV-D的感染率为51.2%,SENV-H为43.9%。结论:SENV可能与HCV和HBV具有一样的传播方式。
Objective: To understand the infection status of SEN virus D / H subtype in different hepatitis patients and blood donors. Methods: SENV-D subtype and H subtype DNA were detected by nested polymerase chain reaction in collected healthy blood donors and patients with various types of hepatitis. Results: The positive rate of SENV-D was 25.9% and the rate of SENV-H was 24.4% in unpaid blood donors. The infection rate of SENV-D in acute hepatitis A was 14.5% and SENV-H was 32.7% The prevalence of SENV-D and SENV-H were 46% and 45.2% for D and SENV-H, respectively. The prevalence of SENV-D in non-A and non-E hepatitis Was 51.2%, SENV-H was 43.9%. Conclusion: SENV may have the same mode of transmission as HCV and HBV.