原发性中枢神经系统淋巴瘤（PCNSL）近10年的发生率有明显的增加,主要好发于接受器官移植病人、免疫抑制病人和先天性免疫缺陷病人。此症无特征性症状及体征,主要表现为颅内占位性病变或弥漫性水肿引起的一系列症状,伴有神经精神方面的改变。目前最常用的诊断方法为立体定向活检术。明确诊断后,可通过化疗联合放疗的方法进行治疗。 The incidence of primary central nervous system lymphoma (PCNSL) in the recent 10 years has increased significantly, mainly in patients receiving organ transplantation, immunocompromised patients and patients with congenital immunodeficiency. No symptoms and signs of this disease and signs, mainly for intracranial space-occupying lesions or diffuse edema caused by a series of symptoms, accompanied by neuropsychiatric changes. The most commonly used diagnostic method for stereotactic biopsy. After a definite diagnosis, it can be treated by chemotherapy combined with radiotherapy.